Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients.
Scientific Abstract
Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective therapeutic intervention in severe Parkinson's disease, its mechanism of action remains unclear. One possibility is that DBS suppresses local pathologically synchronised oscillatory activity.
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Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients.
Scientific Abstract
Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective therapeutic intervention in severe Parkinson's disease, its mechanism of action remains unclear. One possibility is that DBS suppresses local pathologically synchronised oscillatory activity.
Citation
2011.J. Neurol. Neurosurg. Psychiatry, 82(5):569-73.
Free Full Text at Europe PMC
PMC3072048Downloads
Similar content
Preprint
Dithering suppresses half-harmonic neural synchronisation to photic stimulation in humans
Paper
Dopamine and the dynamics of subthalamic and leg muscle activities in parkinsonian stepping.
2025. Brain (e-Pub ahead of print).
Paper
Thalamo-frontal functional connectivity patterns in Tourette Syndrome: Insights from combined intracranial DBS and EEG recordings.
2026. Mol Psychiatry, 31(1):231-242.
Free Full Text at Europe PMC
PMC12700786
Paper
Flexible and stable cycle-by-cycle phase-locked deep brain stimulation system targeting brain oscillations in the management of movement disorders.
2025. Brain Stimul, 18(5):1705-1717.