Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients.
Scientific Abstract
Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective therapeutic intervention in severe Parkinson's disease, its mechanism of action remains unclear. One possibility is that DBS suppresses local pathologically synchronised oscillatory activity.
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Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients.
Scientific Abstract
Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective therapeutic intervention in severe Parkinson's disease, its mechanism of action remains unclear. One possibility is that DBS suppresses local pathologically synchronised oscillatory activity.
Citation
2011.J. Neurol. Neurosurg. Psychiatry, 82(5):569-73.
Free Full Text at Europe PMC
PMC3072048Downloads
Similar content
Paper
Dithering suppresses half-harmonic neural synchronisation to photic stimulation in humans.
2026. Brain Stimul, 19(3):103111.
Free Full Text at Europe PMC
PMC13328066
Paper
Frequency-specific and spatiotemporal dynamics of β-γ phase-amplitude coupling in Parkinson's disease.
2026. Brain (e-Pub ahead of print).
Paper
Characterising motor and cognitive contributions of cortical beta oscillations and their modulation with rTMS.
2026. Neuroimage, 331:121893.
Preprint