Brain stimulation for epilepsy--local and remote modulation of network excitability.
Scientific Abstract
The use of Deep Brain Stimulation (DBS) as a potential therapy for treatment resistant epilepsy remains an area of active clinical investigation. We recently reported the first chronic evaluation of an implantable, clinical-grade system that permits concurrent stimulation and recording, in a large animal (ovine) model developed to study DBS for epilepsy.
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Brain stimulation for epilepsy--local and remote modulation of network excitability.
Scientific Abstract
The use of Deep Brain Stimulation (DBS) as a potential therapy for treatment resistant epilepsy remains an area of active clinical investigation. We recently reported the first chronic evaluation of an implantable, clinical-grade system that permits concurrent stimulation and recording, in a large animal (ovine) model developed to study DBS for epilepsy.
Citation
2014. Brain Stimul. 7(3):350-8
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Flexible and Stable Cycle-by-Cycle Phase-Locked Deep Brain Stimulation System Targeting Brain Oscillations in the Management of Movement Disorders
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Suppression of pathological oscillations with transcranial focused ultrasound in Parkinson’s disease
Nat Commun, Epub ahead of Print (2026)
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A clinical grade neurostimulation implant for hierarchical control of physiological activity
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