Brain stimulation for epilepsy--local and remote modulation of network excitability.
Scientific Abstract
The use of Deep Brain Stimulation (DBS) as a potential therapy for treatment resistant epilepsy remains an area of active clinical investigation. We recently reported the first chronic evaluation of an implantable, clinical-grade system that permits concurrent stimulation and recording, in a large animal (ovine) model developed to study DBS for epilepsy.
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A cardiac pulse signal affects local field potentials recorded from deep brain stimulation electrodes across clinical targets
Brain stimulation for epilepsy--local and remote modulation of network excitability.
Scientific Abstract
The use of Deep Brain Stimulation (DBS) as a potential therapy for treatment resistant epilepsy remains an area of active clinical investigation. We recently reported the first chronic evaluation of an implantable, clinical-grade system that permits concurrent stimulation and recording, in a large animal (ovine) model developed to study DBS for epilepsy.
Citation
2014. Brain Stimul. 7(3):350-8
Similar content
Preprint
Pilot Trial of the Picostim® Deep Brain Stimulation System for Children With Epilepsy: A Prospective, Open-Label Medical Device Study of a System Optimised for Paediatric Neuromodulation
Paper
Post-Ictal Sleep Changes in Human Focal Epilepsy.
2026. J Neurosci, 46(9).
Free Full Text at Europe PMC
PMC12962774
Paper
Towards network-guided neuromodulation for epilepsy.
2022. Brain, 145(10):3347-3362.
Free Full Text at Europe PMC
PMC9586548
Preprint