Denison Group
The Denison Group is based at the Institute of Biomedical Engineering and the Brain Network Dynamics Unit, University of Oxford.
Research Themes
Tools (devices, software, algorithms)
Our research spans three themes: smart implants using closed-loop control for neurotherapies (supporting four clinical studies), non-invasive therapies advancing TMS and memory-reactivation headsets, and resource-limited neurotech developing deployable hardware and algorithms for global healthcare.
Approaches
Experimental Medicine
Active and completed trials (EPIONE, CADET, MINDS, SPARKS) advance experimental medicine by validating adaptive and simplified deep brain stimulation for pain, epilepsy, MSA, and Parkinson’s disease. These studies translate neuroengineering innovation into clinical therapies, bridging lab research and patient care.
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Recent Papers
Post-Ictal Sleep Changes in Human Focal Epilepsy.
2026. J Neurosci, 46(9).
Free Full Text at Europe PMC
PMC12962774
A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe
2026. Neuron (ePub ahead of print).
Dithering suppresses half-harmonic neural synchronisation to photic stimulation in humans.
2026. Brain Stimul, 19(3):103111.
Free Full Text at Europe PMC
PMC13328066
Suppression of pathological oscillations with transcranial focused ultrasound in Parkinson’s disease
Nat Commun, Epub ahead of Print (2026)
Recent Preprints
Pilot Trial of the Picostim® Deep Brain Stimulation System for Children With Epilepsy: A Prospective, Open-Label Medical Device Study of a System Optimised for Paediatric Neuromodulation
A cardiac pulse signal affects local field potentials recorded from deep brain stimulation electrodes across clinical targets
Phase-targeted modulation of essential tremor with transcranial magnetic stimulation of motor cortex
NeuroTest: a benchtop testbed for evaluating sensing-capable electrophysiology and neurostimulation systems
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Group Members
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