Denison Group
The Denison Group is based at the Institute of Biomedical Engineering and the Brain Network Dynamics Unit, University of Oxford.
Research Themes
Tools (devices, software, algorithms)
Our research spans three themes: smart implants using closed-loop control for neurotherapies (supporting four clinical studies), non-invasive therapies advancing TMS and memory-reactivation headsets, and resource-limited neurotech developing deployable hardware and algorithms for global healthcare.
Approaches
Experimental Medicine
Active and completed trials (EPIONE, CADET, MINDS, SPARKS) advance experimental medicine by validating adaptive and simplified deep brain stimulation for pain, epilepsy, MSA, and Parkinson’s disease. These studies translate neuroengineering innovation into clinical therapies, bridging lab research and patient care.
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Recent Papers
A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe
2026. Neuron (ePub ahead of print).
Dithering suppresses half-harmonic neural synchronisation to photic stimulation in humans.
2026. Brain Stimul, 19(3):103111.
Suppression of pathological oscillations with transcranial focused ultrasound in Parkinson’s disease
Nat Commun, Epub ahead of Print (2026)
The Effects of Theta-Gamma Peak Stimulation on Sensorimotor Learning During Speech Production
2025. Neurobiology of Language, 6.
Recent Preprints
Flexible and Stable Cycle-by-Cycle Phase-Locked Deep Brain Stimulation System Targeting Brain Oscillations in the Management of Movement Disorders
A clinical grade neurostimulation implant for hierarchical control of physiological activity
Dithering suppresses half-harmonic neural synchronisation to photic stimulation in humans
Modulation of motor cortical theta and gamma oscillations using phase-targeted, closed-loop optogenetic stimulation of local excitatory and inhibitory neurons
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Group Members
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