Synchronized neural oscillations and the pathophysiology of Parkinson's disease.
Scientific Abstract
Developments in functional neurosurgery for movement disorders and recent advances in electrophysiological techniques have allowed important insights into the role of oscillations in corticobasal ganglia circuits, both in health and in neurological disease states. Here we review recent developments in our understanding of how abnormally synchronized oscillatory activity within the corticobasal ganglia loop may play a key role in the pathophysiology of cognitive and motor phenotypes in Parkinson's disease.
Similar content
Dopamine and the dynamics of subthalamic and leg muscle activities in parkinsonian stepping.
Essential Tremor Disrupts Rhythmic Brain Networks During Naturalistic Movement
Beta Burst Characteristics and Coupling within the Sensorimotor Cortical-Subthalamic Nucleus Circuit Dynamically Relate to Bradykinesia in Parkinson's Disease.
Essential tremor disrupts rhythmic brain networks during naturalistic movement.
Synchronized neural oscillations and the pathophysiology of Parkinson's disease.
Scientific Abstract
Developments in functional neurosurgery for movement disorders and recent advances in electrophysiological techniques have allowed important insights into the role of oscillations in corticobasal ganglia circuits, both in health and in neurological disease states. Here we review recent developments in our understanding of how abnormally synchronized oscillatory activity within the corticobasal ganglia loop may play a key role in the pathophysiology of cognitive and motor phenotypes in Parkinson's disease.