Two sources of dopamine for the hippocampus.

This article describes three recent papers that together suggest that novelty signalling in the brain's memory centre arises from two different brain pathways, whereas up until recently it was thought to originate from only one. Both pathways use a chemical messenger called dopamine.

Scientific Abstract

Dopaminergic signalling is established as playing an important role in novelty related modulation of hippocampal memory. Two recent studies have identified the noradrenergic fibres originating in the locus coeruleus as an additional source of neurotransmitter acting on dopaminergic receptors in the hippocampus.

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Preprint
Causse AA, Curot J, Lopes-Dos-Santos V, Nunes-da-Silva R, Barron HC, Dornier V, Denuelle M, De Barros A, Sol J, Lotterie J, Lehongre K, Fernandez-Vidal S, Frazzini V, Navarro V, Valton L, Barbeau EJ, Denison T, Reddy L, Dupret D

A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe

Two sources of dopamine for the hippocampus.

This article describes three recent papers that together suggest that novelty signalling in the brain's memory centre arises from two different brain pathways, whereas up until recently it was thought to originate from only one. Both pathways use a chemical messenger called dopamine.

Scientific Abstract

Dopaminergic signalling is established as playing an important role in novelty related modulation of hippocampal memory. Two recent studies have identified the noradrenergic fibres originating in the locus coeruleus as an additional source of neurotransmitter acting on dopaminergic receptors in the hippocampus.

Citation

2017. Trends Neurosci., 40(7):383-384.

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PMC5489110

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Similar content

Preprint
Causse AA, Curot J, Lopes-Dos-Santos V, Nunes-da-Silva R, Barron HC, Dornier V, Denuelle M, De Barros A, Sol J, Lotterie J, Lehongre K, Fernandez-Vidal S, Frazzini V, Navarro V, Valton L, Barbeau EJ, Denison T, Reddy L, Dupret D

A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe