Could sleep engineering be used to combat PTSD and depression?
Scientific Abstract
Sleep engineering could be developed to provide a drug-free, non-invasive avenue to treat depression and post-traumatic stress disorder. Such an intervention would be greatly aided by the sophisticated detection of memory reactivations using machine learning classifiers.
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Could sleep engineering be used to combat PTSD and depression?
Scientific Abstract
Sleep engineering could be developed to provide a drug-free, non-invasive avenue to treat depression and post-traumatic stress disorder. Such an intervention would be greatly aided by the sophisticated detection of memory reactivations using machine learning classifiers.
Citation
2026. PLoS Biol, 24(2)e3003633.
DOI
10.1371/journal.pbio.3003633
Free Full Text at Europe PMC
PMC12928472Downloads
Similar content
Paper
Targeted memory reactivation elicits temporally compressed reactivation linked to spindles.
2026. Imaging Neurosci (Camb), 4.
Free Full Text at Europe PMC
PMC12869320
Preprint
Your Emotions, My Brain: Generalizable Neural Signatures of Emotional Memory Reactivation During Sleep
Paper
Disarming emotional memories using targeted memory reactivation during rapid eye movement sleep.
2025. Imaging Neurosci (Camb), 3.
Free Full Text at Europe PMC
PMC12516159
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Targeted memory reactivation in human REM sleep elicits detectable reactivation.
2023. eLife, 12:e84324
Free Full Text at Europe PMC
PMC10425171