Leeha Singh

Dr Leeha Singh is a Paediatric Neurology Subspecialty Trainee with a strong research interest in the mechanisms and treatment of complex childhood epilepsies. She is currently undertaking her PhD within the Thalamic Recordings in Children undergoing SEEG (TRICS) study, based at Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health, under the supervision of Professor Martin Tisdall.

Her doctoral research focuses on defining the neurophysiological signatures of thalamic involvement in paediatric drug-resistant epilepsy (DRE) using intracranial recordings. By analysing thalamocortical network dynamics during seizures, she aims to identify biomarkers that could guide the development of personalised, closed-loop neuromodulation therapies. This work contributes directly to the Core’s broader goal of understanding and harnessing restorative neural dynamics to improve outcomes following neural injury and dysfunction.

Alongside her research, Dr Singh brings rich clinical experience in paediatric neurology, having cared for children with a wide range of neurodevelopmental and epileptic disorders. Clinically, she is passionate about improving outcomes for children with complex and refractory epilepsies. Her previous research has explored seizure, cognitive, and language outcomes following epilepsy surgery in children with Tuberous Sclerosis Complex (TSC), highlighting the importance of early surgical evaluation and multidisciplinary care. She is particularly interested in translational approaches that integrate electrophysiology, imaging, and clinical outcomes to optimise surgical and neuromodulatory interventions for childhood epilepsies.

Through her ongoing research, Dr Singh hopes to contribute to the development of precision therapies that restore network function and improve neurodevelopmental trajectories in children affected by severe epilepsies.